Mathematics and the New Genetics

Paul Decelles. April 17, 2002

Dedicated to Simeon H. Decelles 1912 - 2002

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1. Introduction

2. Mathematics and Genetics are closely intertwined

Example: Analysis of linkage and likelihood ratio tests
3. Quickie Biochemistry
A. Nucleic acids

B. Proteins

4. What we thought we knew:
A. Protein synthesis

B. The central dogma

C. The genetic code

5. Making sense of the genome.
A. The aperiodic crystal

B. Size of the human genome

C. Sequencing the human genome

6. What the human genome is telling us. Early findings.

7. Mathematical applications

8. Trends and implications for education

The Entangled Bank