Step 1.
Cell Body Respose
This starts with the decentralization of the nucleus
Ateegh Al- Arabi, Ph. D.
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Step 1. Cell Body Respose This starts with the decentralization of the nucleus |
Step 2 Metabolic Reaction Increased number of ribosomes around the nucleus. |
Step 3 Immune Ressponse Macrophages start attacking the Schwann cells of the distal segment |
Step 4. Nervous System Reaction All adjacent neurons start extending sprouts of their axons to the target of the injured neuron |
Step 5 Enzymatic Action The axon of the distal segment is broken down by enzymes and the products of the of this action is carried by retrograde transport to the soma |
Step 6 Rapid Cell Division The Shwann cell at the end of the proximal segment starts a rapid mitotic division in attempt to locate the target tissue for the severed neuron |
Step 7 Formation of Growth Path The chain of the Schwann cells that reaches the target tissue will serve as a path for the growth of the axon. |
Step 8 Axon Growth and death of the Extra Schwann cells the remainder of the axon in the proximal tubule starts growing in the tube prepared by the Schwann cells. In the mean time, the Schwann cell s who did not make it to the target cells will start dying phagocytes will take care of heir remains. |
Step 9 Death of Sprouts The re-innervation of the target tissue by the regenerating neuron leads to an automatic death of the sprouts of the adjacent neurons. |
Step 10 Return To Normal After prper and complete of innervation the nucleus return to the center of the soma and the number of the ribosomes declines and the neuron looks normal again. |
| ANIMATED VERSION |
